One guy
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This is a Jerma985 reference

This article contains a reference from Jerma985's streams. These memes transcend many different Twitch channels, and this one in particular has cemented itself as a meme in its own right in Joe's streams.
A "one guy" is a Twitch chatter who gets their message read out by the streamer but is the only person who was saying what they said. A good one guy moment is when a one guy has a significant impact on the stream.